Delayed Posthypoxic Leukoencephalopathy: Improvement with Antioxidant Therapy
نویسندگان
چکیده
منابع مشابه
Delayed Posthypoxic Leukoencephalopathy: Improvement with Antioxidant Therapy.
INTRODUCTION Delayed posthypoxic leukoencephalopathy (DPHL) may result from a variety of hypoxic insults, including respiratory depression from an opiate overdose. The underlying pathophysiological mechanism of DPHL remains uncertain. We describe a patient with a typical case of DPHL who responded clinically to antioxidant treatment. METHODS Clinical, serological, and radiographic investigati...
متن کاملReversible delayed posthypoxic leukoencephalopathy.
Hypoxic ischemic encephalopathy may cause early deep white matter abnormalities on MR imaging that usually progress to include gray matter and basal ganglia change. Toxic leukoencephalopathy due to heroin inhalation predominantly causes cerebellar and posterior cerebral radiologic change. Both conditions rarely present clinically and radiologically in a delayed manner with subsequent recovery. ...
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Article abstract-Delayed demyelination is a rare and poorly understood complication of hypoxic brain injury. A previous case report has suggested an association with mild-to-moderate deficiency of arylsulfatase A. We describe a 36-year-old man who recovered completely from an episode of hypoxia related to drug overdose, and 2 weeks later progressed from a confusional state to deep coma. MRI sho...
متن کاملDelayed posthypoxic leukoencephalopathy: a case series and review of the literature
BACKGROUND Delayed posthypoxic leukoencephalopathy (DPHL) is a rare and underrecognized entity where patients manifest a neurological relapse after initial recovery from an acute hypoxic episode. We sought to describe the magnetic resonance imaging (MRI) findings in a group of patients with DPHL and review the available literature. METHODS Retrospective case series including patients who pres...
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Objective. To describe the clinical, radiological and pathological findings in a patient with methadone-induced delayed posthypoxic encephalopathy (DPHE). Case Report. A Thirty-eight-year-old man was found unconscious for an unknown duration after methadone and diazepam ingestion. His initial vitals were temperature 104 degree Fahrenheit, heart rate 148/minute, respiratory rate 50/minute, and b...
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ژورنال
عنوان ژورنال: Case Reports in Neurology
سال: 2015
ISSN: 1662-680X
DOI: 10.1159/000441892